M77V (p.Met77Val) variant of KRT12 (Keratin, type I cytoskeletal 12)
M77V (p.Met77Val) in KRT12 (Keratin, type I cytoskeletal 12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
M77V (p.Met77Val) variant details
- p.Met77Val
- TOPMed rs1255431749
- gnomAD rs1255431749
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.19
- CADD 0.34
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available