Y74H (p.Tyr74His) variant of KRT10 (Keratin, type I cytoskeletal 10)
Y74H (p.Tyr74His) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data.
Y74H (p.Tyr74His) variant details
- p.Tyr74His
- ExAC rs750559702
- gnomAD rs750559702
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.13
- CADD 14.70
- PolyPhen-2 0.00
- SIFT 0.53
- Most common in the HGDP:FRENCH population (allele frequency 0.019)