S8T (p.Ser8Thr) variant of KRT10 (Keratin, type I cytoskeletal 10)
S8T (p.Ser8Thr) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
S8T (p.Ser8Thr) variant details
- p.Ser8Thr
- gnomAD rs1402109732
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.28
- CADD 8.97
- PolyPhen-2 0.00
- SIFT 0.82
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)