S8R (p.Ser8Arg) variant of KRT10 (Keratin, type I cytoskeletal 10)
S8R (p.Ser8Arg) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data.
S8R (p.Ser8Arg) variant details
- p.Ser8Arg
- TOPMed rs1905494765
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.25
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)