S84I (p.Ser84Ile) variant of KRT10 (Keratin, type I cytoskeletal 10)
S84I (p.Ser84Ile) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data.
S84I (p.Ser84Ile) variant details
- p.Ser84Ile
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.20
- CADD 8.74
- PolyPhen-2 0.01
- SIFT 0.46
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available