S71P (p.Ser71Pro) variant of KRT10 (Keratin, type I cytoskeletal 10)
S71P (p.Ser71Pro) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data.
S71P (p.Ser71Pro) variant details
- p.Ser71Pro
- TOPMed rs1402981926
- gnomAD rs1402981926
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.26
- CADD 17.20
- PolyPhen-2 0.13
- SIFT 0.07
- Most common in the Middle Eastern population (allele frequency 0.0007)