S61R (p.Ser61Arg) variant of KRT10 (Keratin, type I cytoskeletal 10)
S61R (p.Ser61Arg) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data.
S61R (p.Ser61Arg) variant details
- p.Ser61Arg
- gnomAD rs1905470168
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.41
- CADD 15.70
- PolyPhen-2 0.02
- SIFT 0.14
- Most common in the HGDP:YAKUT population (allele frequency 0.04)