S49T (p.Ser49Thr) variant of KRT10 (Keratin, type I cytoskeletal 10)
S49T (p.Ser49Thr) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data.
S49T (p.Ser49Thr) variant details
- p.Ser49Thr
- ExAC rs772718519
- gnomAD rs772718519
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.21
- CADD 17.10
- PolyPhen-2 0.11
- SIFT 0.52
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)