S116R (p.Ser116Arg) variant of KRT10 (Keratin, type I cytoskeletal 10)
S116R (p.Ser116Arg) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data.
S116R (p.Ser116Arg) variant details
- p.Ser116Arg
- ExAC rs781280510
- TOPMed rs781280510
- gnomAD rs781280510
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.36
- CADD 12.70
- PolyPhen-2 0.28
- SIFT 0.27
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)