R86H (p.Arg86His) variant of KRT10 (Keratin, type I cytoskeletal 10)
R86H (p.Arg86His) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as benign/likely benign in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data.
R86H (p.Arg86His) variant details
- p.Arg86His
- rs117610737
- ClinGen CA8548329
- ClinVar RCV001311882
- ClinVar RCV003928836
- Benign/Likely benign
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.33
- CADD 16.70
- PolyPhen-2 0.18
- SIFT 0.15
- ClinVar: Benign/Likely benign (not provided)
- EBI: Benign
- UniProt: Benign
- Most common in the HGDP:FRENCH population (allele frequency 0.019)