R4* (p.Arg4Ter) variant of KRT10 (Keratin, type I cytoskeletal 10)
R4* (p.Arg4Ter) in KRT10 (Keratin, type I cytoskeletal 10) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data.
R4* (p.Arg4Ter) variant details
- p.Arg4Ter
- NCI-TCGA Cosmic COSV9951
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.474
- CADD 35.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)