R15H (p.Arg15His) variant of KRT10 (Keratin, type I cytoskeletal 10)
R15H (p.Arg15His) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as benign in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data.
R15H (p.Arg15His) variant details
- p.Arg15His
- rs28411890
- ClinGen CA8548382
- ClinVar RCV002144601
- 1000Genomes rs28411890
- Benign
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.25
- CADD 18.00
- PolyPhen-2 0.02
- SIFT 0.02
- ClinVar: Benign (not provided)
- EBI: Benign
- UniProt: Benign
- Most common in the 1KG:MSL population (allele frequency 0.013)