R15C (p.Arg15Cys) variant of KRT10 (Keratin, type I cytoskeletal 10)
R15C (p.Arg15Cys) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data.
R15C (p.Arg15Cys) variant details
- p.Arg15Cys
- gnomAD rs1460257467
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- REVEL 0.63
- CADD 23.50
- PolyPhen-2 0.65
- SIFT 0.01
- Most common in the HGDP:YAKUT population (allele frequency 0.04)