L142P (p.Leu142Pro) variant of KRT10 (Keratin, type I cytoskeletal 10)
L142P (p.Leu142Pro) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data.
L142P (p.Leu142Pro) variant details
- p.Leu142Pro
- ExAC rs763494250
- gnomAD rs763494250
- Missense
- Variant Prioritization Score for Impact Estimate 0.54
- REVEL 0.48
- CADD 24.90
- PolyPhen-2 0.66
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)