L142F (p.Leu142Phe) variant of KRT10 (Keratin, type I cytoskeletal 10)
L142F (p.Leu142Phe) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data.
L142F (p.Leu142Phe) variant details
- p.Leu142Phe
- Ensembl rs1031046887
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.29
- CADD 17.80
- PolyPhen-2 0.41
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)