H10N (p.His10Asn) variant of KRT10 (Keratin, type I cytoskeletal 10)
H10N (p.His10Asn) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data.
H10N (p.His10Asn) variant details
- p.His10Asn
- NCI-TCGA Cosmic COSV9950
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.20
- CADD 14.80
- PolyPhen-2 0.00
- SIFT 0.17
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 2.5e-05)