G99A (p.Gly99Ala) variant of KRT10 (Keratin, type I cytoskeletal 10)
G99A (p.Gly99Ala) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data.
G99A (p.Gly99Ala) variant details
- p.Gly99Ala
- TOPMed rs1286205226
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.32
- CADD 15.60
- PolyPhen-2 0.09
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 0.00031)