G96E (p.Gly96Glu) variant of KRT10 (Keratin, type I cytoskeletal 10)
G96E (p.Gly96Glu) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data.
G96E (p.Gly96Glu) variant details
- p.Gly96Glu
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.499
- REVEL 0.47
- CADD 22.60
- PolyPhen-2 0.88
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 0.00048)