G78A (p.Gly78Ala) variant of KRT10 (Keratin, type I cytoskeletal 10)
G78A (p.Gly78Ala) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data.
G78A (p.Gly78Ala) variant details
- p.Gly78Ala
- gnomAD rs1395002512
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.22
- CADD 15.70
- PolyPhen-2 0.14
- SIFT 0.25
- Most common in the African/African-American population (allele frequency 0.00012)