G72D (p.Gly72Asp) variant of KRT10 (Keratin, type I cytoskeletal 10)
G72D (p.Gly72Asp) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data.
G72D (p.Gly72Asp) variant details
- p.Gly72Asp
- ExAC rs756224291
- gnomAD rs756224291
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.40
- CADD 14.30
- PolyPhen-2 0.36
- SIFT 0.08
- Most common in the East Asian population (allele frequency 0.00015)