G60A (p.Gly60Ala) variant of KRT10 (Keratin, type I cytoskeletal 10)
G60A (p.Gly60Ala) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data.
G60A (p.Gly60Ala) variant details
- p.Gly60Ala
- ExAC rs772848992
- gnomAD rs772848992
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.25
- CADD 16.70
- PolyPhen-2 0.66
- SIFT 0.31
- Most common in the East Asian population (allele frequency 0.00015)