G50R (p.Gly50Arg) variant of KRT10 (Keratin, type I cytoskeletal 10)
G50R (p.Gly50Arg) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data.
G50R (p.Gly50Arg) variant details
- p.Gly50Arg
- ExAC rs751529374
- gnomAD rs751529374
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.22
- CADD 18.80
- PolyPhen-2 0.04
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 0.00012)