G23R (p.Gly23Arg) variant of KRT10 (Keratin, type I cytoskeletal 10)
G23R (p.Gly23Arg) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data.
G23R (p.Gly23Arg) variant details
- p.Gly23Arg
- ExAC rs761851864
- gnomAD rs761851864
- Missense
- Variant Prioritization Score for Impact Estimate 0.477
- REVEL 0.39
- CADD 22.30
- PolyPhen-2 0.77
- SIFT 0.02
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)