G22R (p.Gly22Arg) variant of KRT10 (Keratin, type I cytoskeletal 10)
G22R (p.Gly22Arg) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data.
G22R (p.Gly22Arg) variant details
- p.Gly22Arg
- Ensembl rs1905490240
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.28
- CADD 19.70
- PolyPhen-2 0.06
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 0.00041)