G144R (p.Gly144Arg) variant of KRT10 (Keratin, type I cytoskeletal 10)
G144R (p.Gly144Arg) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data.
G144R (p.Gly144Arg) variant details
- p.Gly144Arg
- ESP rs146976249
- ExAC rs146976249
- TOPMed rs146976249
- gnomAD rs146976249
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- REVEL 0.54
- CADD 24.40
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)