G109R (p.Gly109Arg) variant of KRT10 (Keratin, type I cytoskeletal 10)
G109R (p.Gly109Arg) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data.
G109R (p.Gly109Arg) variant details
- p.Gly109Arg
- TOPMed rs1399101061
- gnomAD rs1399101061
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.51
- CADD 15.70
- PolyPhen-2 0.78
- SIFT 0.07
- Most common in the East Asian population (allele frequency 2.5e-05)