G105S (p.Gly105Ser) variant of KRT10 (Keratin, type I cytoskeletal 10)
G105S (p.Gly105Ser) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data.
G105S (p.Gly105Ser) variant details
- p.Gly105Ser
- TOPMed rs1905455888
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.37
- CADD 15.20
- PolyPhen-2 1.00
- SIFT 0.23
- Most common in the HGDP:FRENCH population (allele frequency 0.019)