F94C (p.Phe94Cys) variant of KRT10 (Keratin, type I cytoskeletal 10)
F94C (p.Phe94Cys) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data.
F94C (p.Phe94Cys) variant details
- p.Phe94Cys
- NCI-TCGA Cosmic COSV9950
- Ensembl rs1905462016
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.19
- CADD 18.50
- PolyPhen-2 0.01
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available