F67S (p.Phe67Ser) variant of KRT10 (Keratin, type I cytoskeletal 10)
F67S (p.Phe67Ser) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data.
F67S (p.Phe67Ser) variant details
- p.Phe67Ser
- ExAC rs780082291
- gnomAD rs780082291
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.17
- CADD 18.20
- PolyPhen-2 0.01
- SIFT 0.22
- Most common in the 1KG:CLM population (allele frequency 0.0053)