F57C (p.Phe57Cys) variant of KRT10 (Keratin, type I cytoskeletal 10)
F57C (p.Phe57Cys) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data.
F57C (p.Phe57Cys) variant details
- p.Phe57Cys
- ExAC rs776096107
- gnomAD rs776096107
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.15
- CADD 18.80
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the East Asian population (allele frequency 0.00015)