F122L (p.Phe122Leu) variant of KRT10 (Keratin, type I cytoskeletal 10)
F122L (p.Phe122Leu) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data.
F122L (p.Phe122Leu) variant details
- p.Phe122Leu
- 1000Genomes rs201879590
- ExAC rs201879590
- TOPMed rs201879590
- gnomAD rs201879590
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.20
- CADD 14.10
- PolyPhen-2 0.04
- SIFT 0.60
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)