F102S (p.Phe102Ser) variant of KRT10 (Keratin, type I cytoskeletal 10)
F102S (p.Phe102Ser) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as benign in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data.
F102S (p.Phe102Ser) variant details
- p.Phe102Ser
- rs114467326
- ClinGen CA8548323
- ClinVar RCV002957158
- 1000Genomes rs114467326
- Benign
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.28
- CADD 1.36
- PolyPhen-2 0.00
- SIFT 0.41
- ClinVar: Benign (not provided)
- EBI: Benign
- UniProt: Benign
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)