F102C (p.Phe102Cys) variant of KRT10 (Keratin, type I cytoskeletal 10)
F102C (p.Phe102Cys) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data.
F102C (p.Phe102Cys) variant details
- p.Phe102Cys
- 1000Genomes rs114467326
- ESP rs114467326
- ExAC rs114467326
- TOPMed rs114467326
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.19
- CADD 2.05
- PolyPhen-2 0.00
- SIFT 0.18
- EBI: Benign
- UniProt: Benign
- Most common in the African/African-American population (allele frequency 2.4e-05)