C25F (p.Cys25Phe) variant of KRT10 (Keratin, type I cytoskeletal 10)
C25F (p.Cys25Phe) in KRT10 (Keratin, type I cytoskeletal 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data.
C25F (p.Cys25Phe) variant details
- p.Cys25Phe
- 1000Genomes rs544264740
- ExAC rs544264740
- TOPMed rs544264740
- gnomAD rs544264740
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.18
- CADD 8.29
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the 1KG:MSL population (allele frequency 0.013)