G85D (p.Gly85Asp) variant of KRIT1 (O00522)
G85D (p.Gly85Asp) in KRIT1 (O00522) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
G85D (p.Gly85Asp) variant details
- p.Gly85Asp
- TOPMed rs1307060289
- gnomAD rs1307060289
- Missense
- Variant Prioritization Score for Impact Estimate 0.701
- REVEL 0.65
- CADD 25.60
- PolyPhen-2 0.66
- SIFT 0.00
- Most common in the 1KG:CDX population (allele frequency 0.0057)
- Structural context available