V35F (p.Val35Phe) variant of KMT2E (Histone reader KMT2E)
V35F (p.Val35Phe) in KMT2E (Histone reader KMT2E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
V35F (p.Val35Phe) variant details
- p.Val35Phe
- TOPMed rs1303754526
- gnomAD rs1303754526
- Missense
- Variant Prioritization Score for Impact Estimate 0.611
- REVEL 0.49
- CADD 25.90
- PolyPhen-2 0.81
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available