K86T (p.Lys86Thr) variant of KMT2E (Histone reader KMT2E)
K86T (p.Lys86Thr) in KMT2E (Histone reader KMT2E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
K86T (p.Lys86Thr) variant details
- p.Lys86Thr
- ExAC rs751507681
- gnomAD rs751507681
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- REVEL 0.47
- CADD 24.60
- PolyPhen-2 0.83
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available