A22T (p.Ala22Thr) variant of KIF5A (Kinesin heavy chain isoform 5A)
A22T (p.Ala22Thr) in KIF5A (Kinesin heavy chain isoform 5A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A22T (p.Ala22Thr) variant details
- p.Ala22Thr
- gnomAD rs1371053668
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.12
- CADD 22.40
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available