S8C (p.Ser8Cys) variant of KIF11 (Kinesin-like protein KIF11)
S8C (p.Ser8Cys) in KIF11 (Kinesin-like protein KIF11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
S8C (p.Ser8Cys) variant details
- p.Ser8Cys
- gnomAD 10-92593398-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.18
- CADD 22.60
- PolyPhen-2 0.63
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available