S7L (p.Ser7Leu) variant of KIF11 (Kinesin-like protein KIF11)
S7L (p.Ser7Leu) in KIF11 (Kinesin-like protein KIF11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
S7L (p.Ser7Leu) variant details
- p.Ser7Leu
- gnomAD 10-92593395-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.17
- CADD 24.70
- PolyPhen-2 0.15
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available