S36R (p.Ser36Arg) variant of KIF11 (Kinesin-like protein KIF11)
S36R (p.Ser36Arg) in KIF11 (Kinesin-like protein KIF11) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S36R (p.Ser36Arg) variant details
- p.Ser36Arg
- 1000Genomes rs199698837
- ExAC rs199698837
- TOPMed rs199698837
- gnomAD rs199698837
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.33
- CADD 9.37
- PolyPhen-2 0.68
- SIFT 0.01
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available