K60R (p.Lys60Arg) variant of KIF11 (Kinesin-like protein KIF11)
K60R (p.Lys60Arg) in KIF11 (Kinesin-like protein KIF11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
K60R (p.Lys60Arg) variant details
- p.Lys60Arg
- gnomAD 10-92606366-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.40
- CADD 26.90
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available