I40T (p.Ile40Thr) variant of KIF11 (Kinesin-like protein KIF11)
I40T (p.Ile40Thr) in KIF11 (Kinesin-like protein KIF11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
I40T (p.Ile40Thr) variant details
- p.Ile40Thr
- gnomAD 10-92606306-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.532
- REVEL 0.56
- CADD 26.40
- PolyPhen-2 0.80
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available