I19T (p.Ile19Thr) variant of KIF11 (Kinesin-like protein KIF11)
I19T (p.Ile19Thr) in KIF11 (Kinesin-like protein KIF11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
I19T (p.Ile19Thr) variant details
- p.Ile19Thr
- gnomAD 10-92593431-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.767
- REVEL 0.84
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available