F28L (p.Phe28Leu) variant of KIF11 (Kinesin-like protein KIF11)
F28L (p.Phe28Leu) in KIF11 (Kinesin-like protein KIF11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
F28L (p.Phe28Leu) variant details
- p.Phe28Leu
- TOPMed rs1242282875
- gnomAD rs1242282875
- Missense
- Variant Prioritization Score for Impact Estimate 0.546
- REVEL 0.50
- CADD 23.20
- PolyPhen-2 0.31
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available