E14K (p.Glu14Lys) variant of KIF11 (Kinesin-like protein KIF11)
E14K (p.Glu14Lys) in KIF11 (Kinesin-like protein KIF11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
E14K (p.Glu14Lys) variant details
- p.Glu14Lys
- gnomAD 10-92593415-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.18
- CADD 25.70
- PolyPhen-2 0.24
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available