D59E (p.Asp59Glu) variant of KIF11 (Kinesin-like protein KIF11)
D59E (p.Asp59Glu) in KIF11 (Kinesin-like protein KIF11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
D59E (p.Asp59Glu) variant details
- p.Asp59Glu
- gnomAD 10-92606364-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.35
- CADD 16.50
- PolyPhen-2 0.18
- SIFT 0.15
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available
- Literature evidence available