T36N (p.Thr36Asn) variant of KEAP1 (Q14145)
T36N (p.Thr36Asn) in KEAP1 (Q14145) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
T36N (p.Thr36Asn) variant details
- p.Thr36Asn
- Ensembl rs2144630406
- Missense
- Variant Prioritization Score for Impact Estimate 0.428
- REVEL 0.21
- CADD 21.90
- PolyPhen-2 0.27
- SIFT 0.25
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available