T36A (p.Thr36Ala) variant of KEAP1 (Q14145)
T36A (p.Thr36Ala) in KEAP1 (Q14145) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T36A (p.Thr36Ala) variant details
- p.Thr36Ala
- cosmic curated COSV50637
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.32
- CADD 16.30
- PolyPhen-2 0.04
- SIFT 0.85
- Most common in the Non-Finnish European population (allele frequency 8.1e-06)
- Structural context available