G26R (p.Gly26Arg) variant of KEAP1 (Q14145)
G26R (p.Gly26Arg) in KEAP1 (Q14145) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
G26R (p.Gly26Arg) variant details
- p.Gly26Arg
- ExAC rs761466505
- gnomAD rs761466505
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.31
- CADD 21.90
- PolyPhen-2 1.00
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available